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Side effects vary from person to person and depend on many factors, including dosage, treatment duration, overall health, and individual sensitivity

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Considering that inflammation is a key factor in many diabetic complications, these anti-inflammatory effects of semaglutide could provide additional benefits, particularly in the cardiovascular system [66]

In a phase 2, randomized, double-blind, placebo-controlled trial (NCT04881760) involving adults with obesity without type 2 diabetes, retatrutide (1 mg12 mg weekly) produced dose-dependent weight loss of up to 24.2% from baseline at 48 weeks, compared with 2.1% with placebo