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Possible side effects may include mild nausea, flushing, or a temporary metallic taste, but most side effects are rare and short-lived

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Ipamorelin produced a selective and dose-dependent increase in GH levels with no significant stimulation of ACTH or cortisol, suggesting hypothalamic specificity. Kraemer et al., Journal of Clinical Endocrinology & Metabolism 2

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For the cell experiments, all cell samples were randomly coded by an independent third party, and experimenters conducted treatments and measurements without knowledge of the specific group assignments

These are mechanistically different agents at opposite ends of the regulatory ladder