[DOI] [PubMed] [Google Scholar] [21].Groschwitz KR, Hogan SP
These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2
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Weight loss of 10% or more may necessitate levothyroxine dose adjustments, and patients should be educated to recognise symptoms of both hypothyroidism (fatigue, cold intolerance, constipation) and hyperthyroidism (palpitations, anxiety, tremor) that might indicate the need for dose modification
Its upregulation of antioxidant enzyme expression, including superoxide dismutase and catalase, has also been a subject of research interest
