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Acute musculoskeletal injuries (tendon strains and muscle tears) show functional improvement from 2 to 4 weeks, while full collagen remodeling requires 4 to 6 weeks of consistent administration

Frataxin deficiency is associated with imbalances in iron-sulfur containing proteins, mitochondrial respiratory chain dysfunction and lower ATP production, and accumulation of iron in the mitochondria, which increases oxidative stress and oxidative damage to macromolecules of the respiratory chain (77)

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Formulation and in vitro evaluation of topical nanoemulsion and nanoemulsion-based gels containing daidzein

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Braakhuis et al