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Orlistat does not affect hunger, but it can help with weight loss when paired with a low-fat diet

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Additionally, GLP-1 agonists influence gastric emptying, which could interact with psychiatric medication pharmacokinetics, altering their effectiveness or safety, especially those with weight-based dosing

Alcohol: Can contribute empty calories and interfere with medication effects

Clinical guidelines generally support longer-term use for sustained outcomes, but the appropriate duration for how long to take GLP-1 medication should be guided by a prescriber based on individual goals, response to treatment, and overall health

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