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New indications and more players in the field The number of indications for GLP-1s continues to grow steadily, like Ozempics recent approval for adults with type 2 diabetes and chronic kidney disease, as well as benefits beyond weight and blood sugar management (e.g., peripheral artery disease, liver disease, heart disease , sleep apnea, osteoarthritis)

PTD-DBM does not

doi: 10.1016/j.cmet.2021.01.015

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and stimulation of the pro-fibrotic pathway (166), which may contribute to pathological remodeling of cardiovascular tissue

When used for weight loss, semaglutide is typically administered as a weekly injection or shot