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Endotoxin contamination a common source of confounding in peptide research can trigger inflammatory responses in biological assays that mimic or mask the compounds actual biological activity

They illustrated that 80 mg/d pyridoxine supplementation during 12 weeks reduced the headache diary results (HDR), severity, and duration of migraine attacks, compared with the placebo (59)

10 Simone DA, Ngeow JYF, Putterman GJ, LaMotte RH

The MHRA guidance on supplying unlicensed medicines is explicit: an unlicensed product may only be supplied to meet the special clinical needs of an individual patient where a licensed equivalent cannot, and the prescriber carries full responsibility

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