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Headache, particularly at initiation Mild anxiety or restlessness with some compounds Nasal irritation (intranasal administration) Sleep disturbance if dosed too close to bedtime Rare: Mood changes or emotional lability Dihexa (PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent hepatocyte growth factor (HGF) receptor agonist originally developed at Washington State University

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No Known Effects: No serious side effects have been reported with the use of injectable vitamin B12 in animals

Dihexa was developed as a structurally modified analogue of angiotensin IV and retains key features of the parent scaffold while incorporating modifications designed to alter physicochemical and pharmacological properties

Mar 2019;8(1):14-21

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