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On one hand, iron overload markedly enhances the accumulation of reactive oxygen species (ROS) in cerebral endothelial cells, leading to downregulation of ferroportin 1 (FPN1) and impaired iron efflux
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Neurobiol Aging 26(3):349354 Mnch G, Robinson SR (2002b) Comment on Vicki Browers article Harnessing the immune system to battle Alzheimers in EMBO reports, March 2002
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