Most side effects are gastrointestinal and tend to be mild to moderate, often occurring when the dose is increased
In the Phase 2 obesity trial published in NEJM in 2023, retatrutide at the 12 mg weekly dose produced a mean placebo-adjusted body weight reduction of 22.1 percentage points (22.1% (24.2% arm) mean absolute reduction on the retatrutide arm) at 48 weeks (Jastreboff et al., NEJM, 2023)
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Rated 5 out of 5 Tracy (verified owner) At 57 (almost 58) I was keeping track of and measuring everything I ate, along with walking everyday, but was at a plateau and my weight wouldnt budge
Properly stored, it lasts 28-30 days refrigerated
How long a medication lasts is always an important question, but when you're paying hundreds of dollars for a single pen, the idea of throwing away "perfectly good" medication feels downright wasteful