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Therefore, limiting patient recruitment to one group of DMARDs is not feasible as it will result in a non-representative patient selection

The degree of absorption delay varies between individuals based on semaglutide dose, duration of treatment, and personal metabolic factors

30712, H1764H1776

In addition, it needs to be established whether the differential toxicity observed in liver slices can be reproduced using isolated hepatocytes, or in other in vitro models

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Its also worth noting that GLP-1s can have challenging side effects that are mostly GI-related, like vomiting, nausea, diarrhea, and constipation