LJ: Conceptualization, Visualization, Writing review & editing
Disease activity appears to correlate with the level of this marker
Vitamin B12 shots are generally safe during pregnancy, especially if you have a deficiency in B12
A phase 2, proof of concept, randomised controlled trial of berberine ursodeoxycholate in patients with presumed non-alcoholic steatohepatitis and type 2 diabetes
The structural basis for this triple activity was elucidated through 2024 cryo-EM studies, which showed that retatrutides 26-amino acid backbone adopts distinct helical conformations at each receptor interface, explaining how balanced agonism across all three receptors is achievable without sacrificing binding affinity at any single target [9]
This precision approach helps prioritize which strategiesdietary, behavioral, or pharmacologicalalign best with individual biology