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The trial results at the 52nd week of a 54-month randomized, double-blind, placebo-controlled study (NCT03900429) involving Resmetirom were subsequently published [92]

As a potent dual receptor agonist, this compound is extensively studied for its synergistic interaction with both the GLP-1 (Glucagon-like Peptide-1) and GIP (Glucose-dependent Insulinotropic Polypeptide) receptor pathways

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If energy feels limited, reducing workout length or increasing rest between sets can help maintain consistency without excessive fatigue

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The alternative to tirzepatide would depend on the specific medical condition it is being used to treat