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The Phase 2 trial followed participants through 48 weeks of treatment but did not include an extended washout observation period comparable to longer post-trial data available for Semaglutide

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Resistin levels are higher during asthma exacerbations, as compared to healthy controls, but not during their resolution or follow-up [183]

The combination arm was terminated early due to severe adverse events and deaths, while NAC alone showed no significant effect on lung function, though secondary endpoints (6MWD, QoL) improved modestly (139)

Persisting hyperglycaemia despite basal insulin titration with predominantly postprandial hyperglycaemia requires additional rapid-acting insulin administrations either as rapid-acting insulin injection or incorporated in premixed insulins