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Reports of short-term tolerance exist in small observational settings, yet these reports lack randomized control, large populations, and multi-year follow-up

Some people are under the misconception that building a tolerance keeps a person from experiencing the negative effects of alcohol or other substances, when in reality, the more of a substance they use, the more damage they are doing to their mental and physical health

We cant say that GLP-1s are actually causing these symptoms, notes Neil Sehgal, the studys first author and a doctoral student in CIS advised by Guntuku and Ungar

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