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Maybe they tire sooner

It works by mimicking two essential hormones that naturally manage appetite and blood sugar levels: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

Yet obesity can affect how medications are absorbed, distributed, metabolized, and eliminated in the body

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But certain situations push patients to look elsewhere: You want ongoing provider check-ins

Additionally, real-world pharmacovigilance data highlight sensory adverse events (particularly dysgeusia) that appear more frequently in clinical practice than in controlled trials, suggesting under recognition of taste-related disturbances in research settings (159)