Glutathione might inhibit the effects of cerebral infarction and enhance antiapoptotic signaling after ischemic stroke, suggesting that GSH may be a potent therapeutic antioxidant that can attenuate severe pathologies after ischemic stroke, and stimulating GSH synthesis through administration of GSH precursors and micronutrients like selenium can optimize GSH and GSH peroxidase for optimal antioxidant defense in cerebral ischemia (155, 156)
Central to liver Phase II detoxification
Too much hydrogen sulfide may also be linked to adrenal insufficiency due to H2S helping to control mitochondrial function in the adrenal tissue (Wang et al., 2014)
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studies used weight-based dosing of approximately 100 mg/kg/day each of glycine and NAC, which for a 70 kg adult translates to approximately 7 g glycine + 7 g NAC daily, taken in divided doses [10][21]
Published in Life Sciences (2007;80:13511355)