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Methods: RAPIDe-1 (NCT04618211) was a double-blind, placebo-controlled, crossover, phase 2 trial evaluating the efficacy and safety of deucrictibant IR capsule (10 mg, 20 mg, or 30 mg) for treatment of HAE attacks

Drugs: a tangled web of targets

297,307 In addition, astrocytes lose AQP4 channels in their endfeet and down-regulate expression of glutamate transporters, thus adding to excitotoxic damage of oligodendrocytes

Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome