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We generated and characterised the first Ubx-RNA binding mutant and demonstrated the critical function of Ubx-RNA binding in splicing regulation

1 An alternative mechanism by which medications may enhance APAP hepatotoxicity involves competitive utilization of the glucouronidation pathway, resulting in increased metabolism towards the CYP system and thus enhanced formation of hepatotoxic substrates

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COX2 is expressed at low levels in most tissues but can be highly expressed in response to various stimuli, including inflammatory mediators and tumor promoters [46]

doi:10.1016/j.mehy.2013.08.024 14