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The PDUFA target action date is 7 July 2026

Mechanism [edit] Glutathione synthase catalyzes the chemical reaction ATP + gamma-L-glutamyl-L-cysteine + glycine ADP + phosphate + glutathione The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and glycine, whereas its 3 products are ADP, phosphate, and glutathione

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Best dose gave 44% response / 32% remission vs 32% / 20% for placebo described by the authors as numerically higher, i.e

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