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However, by the early 1970s, the use of both PMB and CST was largely discontinued because of their significant neurotoxicity and nephrotoxicity [12]

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At the same time, global prevalence and burden of mental disorders continue to rise exponentially, placing great strain on our health systems

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However, downstream effects such as body composition changes, improved sleep quality, or visceral fat reduction typically require consistent administration over several weeks to months of research