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[69] found that high concentrations of calcium and phosphate were able to inhibit the SLC7A11/GSH/GPX4 pathway in rat vascular smooth muscle cells, thereby inducing ferroptosis
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327,328 Combining FK866 with the PARP inhibitor, olaparib, results in cell death through the suppression of the NAD + serving as the substrate of PARP in triple-negative breast cancer or colon cancer cell lines as well as in vivo models, with the combinatorial treatment inducing negligible systemic