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Homozygotes and heterozygotes can be symptomatic, although the disease typically is more severe in persons who are homozygous for the deficiency

Supportive immune function: The immune-modulating effects of high-dose vitamin C help support immune function during cancer treatment when immune systems are often compromised

Furthermore, -HB binding to HCA1 or fatty acids binding to the G proteincoupled receptor 40 (GPR40) enhances the expression of the scaffold protein -arrestin-2 (ARRB2)

Subsequently, supplementary B12 may be necessary

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