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523 Analysis of gene expression in cortical astrocytes from old mice identified an increase in genes linked to an immune response with a decrease in expression of GFAP and genes related to neuroprotection and neuronal support, 524 and the prominent up-regulation of genes contributing to synapse elimination in astrocytes from aged hippocampus and cerebellum

Next, we tested the replicative capacity of C2C12 cells following prolonged metabolic stress as a functional marker of protection

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Patients experiencing persistent or severe body aches should discuss these symptoms with their prescribing clinician to ensure appropriate assessment and management