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For instance, AMG 337, a potential and highly selective small molecule Met kinase inhibitor, significantly decreases tumor growth of Met-high-expression and Met-amplified HCC cell lines in in vitro and in vivo trials (Luo et al., 2019)

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But since thiols also have a high affinity for heavy metals we can see how mercury exposure from amalgams for instance can interfere with the functions of iron and zinc in the body

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