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From the previous study, it was observed that for an individual with chronic stage omega-3 fatty acid deficiencies, changes in the concentration of brain fatty acids can result in an altered serotonergic or dopaminergic neurotransmission, increase in 5-HT2, 27 and decrease in serotonin and dopamine in the prefrontal cortex, 29 thereby indicating the importance of adequate PUFA intake

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But because psoriasis is a systemic immune condition, systemic delivery may be necessary to address the underlying immune dysregulation

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