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Description

In contrast, re-expression of MAPKAPK2 reversed these alterations, restoring Nrf2 nuclear localization and enhancing HO-1 expression (Figure 7D), consistent with activation of an antioxidant defense response

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Legal Status Like many experimental peptides, Dihexa is not FDA-approved and has never been advanced into formal human clinical trials

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Science 282 , 103107 (1998)

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Thus, GSH plays a critical role in the restoration of cell signaling and transcriptional program during cystine starvation in HepG2 cells

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