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7 Limitations Although increasing evidence indicate natural supplements as effective anticancer agents, several deficiencies impede their clinical translation and generalization

Additionally, PRDX6 acts as a selenium-binding protein that promotes efficient intracellular selenium utilization, thereby sustaining GPX4 expression and activity and indirectly enhancing resistance to ferroptosis (Ito et al., 2024)

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Additionally, oxidative damage, driven by ROS and biometals like iron, plays a significant role in the diseases progression (544)

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biognesis in muscle cells