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Diabetic neuropathy, a common complication, is characterized by nerve damage, particularly in the peripheral nervous system

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They must ensure quality in new manufacturing sites (inspections of multi-billion-dollar plants are scheduled), authorizing tech transfers, and approving new dosage forms

Similarly, we can assay samples pre- and post-treatment for biomarkers that associate with drug response, such as those reading out improvements in glycemic control and endothelial function

Finally, amelioration of the G/F-actin ratio restores the disruption of the YAP signal induced by high glucose and upregulates the transcription factors Neurod1, Foxa1, and Foxa2, which are responsible for controlling L-cell differentiation [30] (Fig

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