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The underlying mechanism of such drugs is reported to have a multi-mechanistic or physiological approach through inhibiting the renin-angiotensin system

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Kapoor G, Saigal S, Elongavan A

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Hcy-thiolactone/creatinine ratio was indicated as a novel acute myocardial infarction risk predictor in patients with suspected coronary artery disease, independent of traditional risk factors and Hcy, but modified by vitamin B6 catabolism 9