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PlexusDx recognizes that tirzepatide's effectiveness stems partly from altered gut-brain signaling, which can create a window of opportunity for behavioral change

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During angiogenesis, the trafficking of integrins dictates the deposition of the extracellular matrix

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The lessons learned from astrocyte-targeted strategies provide a natural transition to examining microglia, whose dual role as immune defenders and potential drivers of pathology makes them equally compelling therapeutic targets (Figure 5)