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Activated platelets with an increased mean volume [mean platelet volume (MPV)] secrete microparticles (MPs) and soluble adhesion molecules (e.g., sP-selectin and sCD40L) that in turn activate endothelial and immune cells (6769)

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A study in the Journal of Pharmaceutical and Biomedical Analysis found that semaglutide exposed to room temperature (25C) loses 10-15% potency per month compared to refrigerated storage