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Acknowledgements The authors thank the Cloning, Cell Expression, Protein Purification and Assay Development Core Facilities of iHuman Institute for their support

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Regulation of Nrf2-BDNF activation and expression is demonstrated by in vitro treatment of BV-2 cells with emodin and omega-3 docosapentaenoic acid, which promote BDNF expression, potentially through elevation of Nrf2 transcription (Liu et al., 2021