glutathione in diabetes Efficacy and Safety of Supplementation Type 2 & Diabetes Complications Dietary Supplements Potentially Target Plasma

10.1073/pnas.1612262113 Proc Natl Acad Sci U S A

doi:10.1007/s12264-018-0269-8 22

PMCID: PMC3434320.10.1038/ki.2012.176 [PMC free article: PMC3434320] [PubMed: 22622492] [CrossRef] 37

Key findings include: Dose-dependent improvements in neurological function scores at doses 2.5 ml/kg in rat models Reduced infarct volumes in middle cerebral artery occlusion (MCAO) models Enhanced functional recovery when combined with rehabilitation protocols Protection against excitotoxicity and oxidative stress in acute phase Studies using embolic stroke models showed that Cerebrolysin at 5 ml/kg significantly reduced lesion volume and improved sensorimotor outcomes when treatment began 4 hours post-stroke[8]

Sessions generally last 30 to 60 minutes in professional clinics or IV lounges

After 8 weeks, there were no significant differences between groups in change of muscle strength