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Glutamate accumulation to micromolar levels [375] results in GluN2B-mediated NMDA receptor overactivation, Ca 2+ overload, and subsequent tau hyperphosphorylation and dendritic spine collapse [376], linking excitotoxicity to amyloidogenesis [28]
Cancers in Australia in 2010 attributable to and prevented by the use of combined oral contraceptives
Larazotide works complementarily by binding claudin receptors to restore the tight-junction barriers that, when compromised, allow bacterial endotoxins from periodontal pathogens to penetrate systemic circulation
The benzyl alcohol preservative inhibits bacterial growth, allowing the same vial to be used over several days or weeks without contamination
DOI:10.1158/1055-9965.epi-05-0105 [ Links ] 55
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