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The proposed mechanism considering dipeptides rather than single monomers as the basic modules in tetradepsipeptide assembly and oligomerization of tetradepsipeptides to give octa- and dodecadepsipeptides is well in line with the higher abundance of tetra-, octa- and dodecadepsipeptide esters released upon ethanolysis when compared to di-, hexa- and decadepsipeptide esters (Fig

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5 cGAS-STING signaling: a target for RA treatment According to the above description, cGAS-STING signaling primarily plays a pathogenic role in RA