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Global surveillance, prevention and control of chronic respiratory diseases: a comprehensive approach

The overall discontinuation rate in clinical trials was approximately 8.1%, primarily due to nausea

Among them, oxidative stress refers to the excessive accumulation of reactive oxygen species (ROS) that leads to the imbalance of oxidants and antioxidants, oxidative stress has the ability to lead to mitochondrial dysfunction and lysosome dysfunction, and ultimately induces neurodegenerative disease (Caspersen et al., 2005

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This evidence may argue against the role of long-chain acyl-CoAs in controlling GSIS

Most issues resolve with concentration reduction or application frequency adjustment