Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
Without angiogenesis, repair is mechanically limited regardless of how many cells are mobilized
Unlike the continuous capillaries in the heart (22) and the sinusoidal capillaries in the liver (23), the capillaries in the glomerulus are fenestrated, including pores that allow the penetration of small molecules but restrict the diffusion of proteins
A key challenge is optimizing the bioavailability and pharmacokinetics of these compounds for oral administration in humans
Contact a maternal-fetal medicine specialist for enhanced prenatal surveillance including high-resolution anatomy scans at 1820 weeks and fetal echocardiography
Li Y, Li A, Glas M, Lal B, Ying M, Sang Y, Xia S, Trageser D, Guerrero-Cazares H, Eberhart CG, et al