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TB-500 represents an intriguing area of emerging clinical application for long COVID patients dealing with any of the following concerns: Neurological symptoms Cognitive impairment Tissue damage associated with prolonged inflammation KPV and Immune-Gut Axis Modulation KPV is a tripeptide derived from alpha-melanocyte-stimulating hormone (alpha-MSH) with potent anti-inflammatory effects, particularly in the gut

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Importantly, even if variable in %, coffee represents the richest dietary source of CGAs [10]