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In fact, Mansour [31] reported that a high dose (250 mg/kg body wt) of ALC significantly increase glutathione peroxidase and SOD activities in the lungs and livers of rodents, and Calabrese et al

So when I prescribe 1000 mcg daily, I am giving a large dose knowing that the absorption fraction is small

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Now, the other reason why I think this is an important concept that goes beyond cancer but now gets to the broader aspect of aging is, when you look at the people who live the longest, when you look at these people who live to 100 and beyond, for the most part they die of the exact same diseases as the rest of us schleps