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Melatonin can exert its effects by acting through specific cellular receptors on the plasma membrane, similar to other hormones, or through receptor-independent mechanisms that involve complex molecular cross talk with other players

Cannell JJ

GLP-1 binds to GLP-1Rs expressed in multiple organs, including the pancreas, liver, gastrointestinal tract and brain, exerting pleiotropic effects such as enhancing insulin secretion (18), reducing blood glucose levels, suppressing GCG release (19), delaying gastric emptying (16), decreasing food intake (20), promoting weight loss and providing cardiovascular protection (21,22)

Without sufficient levels of this antioxidant, the liver may struggle to process the daily load of environmental exposures we all encounter

The -glutamyl cycle requires the use of three ATP molecules per turn of the cycle

In vitro BBB models are widely used to study BBB physiology and the cellular mechanisms involved in this barrier as it can be readily manipulated