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The recommended daily intake (RDI) of vitamin B12 for adults over 19 is Deficiency is common, especially in people who follow a vegetarian or vegan diet

Route/evidence mismatch: the pivotal mouse study tested subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) the oral capsule use that is actually sold and discussed commercially has not itself been directly tested in that published research

Stomach acid plays a critical role in separating vitamin b12 from dietary proteins, the first step in b12 absorption

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While current research does not show a notable reduction in B12 absorption, the changes in digestion could affect the absorption of nutrients, making it important to take supplements, including vitamin B12