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For example, excessive doses of the copper ionophore elesclomol can flood cells with copper, overwhelming antioxidant defenses and triggering lethal oxidative stress [247] whereas excessive copper supplementation can cause overload and ROS-mediated damage [248]

In clinical trials, participants taking the oral formulation lost an average of 13.6% of their body weight over 64 weeks

Further experiments are required to establish the exact mechanisms leading to the changes in cell proliferation and differentiation upon combined treatment and whether they are linked to alterations in COX2-PGE 2 pathway and/or to mimicry of paracetamol overdose

Copper has wound healing properties due to its role in creating new blood vessels and tissue repair

ensure that patient maintains adequate fluid intake

A case report looking at the effects of faecal microbiota transplantation in a patient with bipolar disorder