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Ponies undergoing maximal exertion on a treadmill were found to have significant vasoconstriction of the renal and splanchnic vascular beds and resultant decreases in blood flow to the spleen, pancreas, small intestine, and colon, among other organs [48]

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Epigallocatechin-3-O-gallate (EGCG) is the most active and abundant polyphenol in green tea ( In an UUO mice model, EGCG was found to attenuate renal fibrosis by inhibiting the accumulation of ECM and EMT, and this renoprotective effect might be associated with its effect of the alleviation of inflammatory responses and TGF-/Smad signaling pathway inhibition (Wang et al., 2015a)

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