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One retrospective study published in the International Journal of Obesity found that patients who added this combination to their existing GLP-1 regimen saw additional weight loss

Although metformin is a common drug for managing DM, however, monotherapy treatment with any antidiabetic drug will necessitate dosage increment since type 2 DM (T2DM) deteriorates over time due to the increasing pancreatic -cell dysfunction and will eventually require a combination therapy approach with another antidiabetic medication

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Iskusnykh IY, Popova TN, Agarkov AA et al (2013) Expression of glutathione peroxidase and glutathione reductase and level of free radical processes under toxic hepatitis in rats

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