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There were no cases of glucose intolerance, insulin resistance, edema (fluid retention), joint pain, carpal tunnel syndrome, or other manifestations of excess growth hormone activity

Naturally aged mice exhibited significantly lower sperm concentration and motility compared to young mice , confirming age-related declines in sperm quality

That connection is central to traceability

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2017 Cell study, with subsequent independent confirmations in human chondrocytes (Huang 2021), mouse Leydig cells (Zhang 2020