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In the phase 2 trial published in the New England Journal of Medicine, participants on the 12mg dose saw liver fat reductions of up to 82.4%

Here is what the published research actually looks at for each one

But the status quo, he argued, is no better

The lack of knowledge concerning the effectiveness of vonoprazan in other therapeutic regimens is a gap which could be filled by future studies (Jung et al., 2017)

FDA staff had recommended against including emideltide, which is used for insomnia and opioid withdrawal, on the list in part because studies on its efficacy are limited and because there are alternative therapies available to treat those conditions

Unknown effects from extended or repeated use cannot be ruled out