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The final supernatant (100 L) was used for LC-MS analysis

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However, it took an average of four years for them to regain their lost kilos

Notably, this pathway can be reversed by activating YAP1 through MST1/2 inhibition, which shifts macrophages from an M2 to an M1 phenotype, enhancing CD8+ T-cell activity and mitigating tumor progression

doi: 10.1603/0022-0493-98.3.656 73