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10.1016/j.jep.2023.117659 171 WangY.WangS.XinY.ZhangJ.WangS.YangZ.et al (2021b)

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The activation of HO-1, a mitochondrial enzyme that catalyses the degradation of haem to generate ferrous iron, results in increased mitochondrial iron, thereby upregulating ferroptosis [139, 140]

Importantly, the heterologous expression of SsCm1 into yeast aro7 mutant could not restore the ability of yeast to synthesize tyrosine and phenylalanine (Fig

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