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Similarly, in hepatocytes exposed to lipotoxic stressors, zinc supplementation reduces cytotoxicity by mitigating ER stress and enhancing antioxidant defense, demonstrating its capacity to preserve proteostasis and limit inflammatory responses 178

Patients with obesity who want a more durable solution, who qualify for bariatric surgery, or who are concerned about the long-term cost and sustainability of GLP-1 medications may want to consider gastric sleeve

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